Product Name :
PRPF4 Recombinant Rabbit Monoclonal Antibody [JE65-37]
Predicted band size :
58 kDa
Observed band size :
58 kDa
Synonyms:
hPrp4 antibody HPRP4P antibody PRP4 antibody PRP4 homolog antibody PRP4 pre mRNA processing factor 4 homolog (yeast) antibody PRP4/STK/WD splicing factor antibody PRP4_HUMAN antibody Prp4p antibody PRPF4 antibody RP70 antibody 展开
Function :
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF4 is 1 of several proteins that associate with U4 and U6 snRNPs.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human PRPF4 aa 1-50/522.
Species reactivity:
Human
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
JE65-37
RRID:
AB_3072187
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Benzene-1,3,5-tricarbaldehyde Purity Aliquot store at -20℃.(R)-N-Fmoc-2-(7-octenyl)Alanine manufacturer Avoid repeated freeze / thaw cycles.PMID:33719698
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 58 kDa
Positive control :
HT-29 cell lysate, SW480 cell lysate, MCF-7 cell lysate, SiHa, human cervical carcinoma tissue, human colon tissue, H1395.