Product Name :
ORC1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
HSORC1 antibody MmORC1 antibody orc1 antibody ORC1_HUMAN antibody ORC1L antibody Origin Recognition Complex 1 antibody Origin recognition complex subunit 1 (yeast homolog) like antibody Origin recognition complex subunit 1 antibody Origin recognition complex subunit 1 homolog antibody Origin recognition complex subunit 1 like (S. cerevisia antibody 展开
Function :
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex.Methyl 1H-1,2,3-triazole-4-carboxylate site While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing.183070-44-2 In stock Alternatively spliced transcr
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human ORC1L.PMID:33595373 AA range:331-380
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
97 kDa
Positive control :
Epithelium,Eye,