Product Name :
SRY Mouse Monoclonal Antibody [E9-G4]
Predicted band size :
Observed band size :
Synonyms:
Essential protein for sex determination in human males antibody Sex determining region on Y antibody Sex determining region protein antibody Sex determining region Y antibody Sex-determining region Y protein antibody sox21b antibody SRXX1 antibody SRXY1 antibody SRY 1 antibody SRY antibody 展开
Function :
SRY (sex-determining region Y protein) is a tran-scriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.3-Azidopropanoic acid Formula
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
E9-G4
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.Formula of 731810-57-4
Storage buffer solution:
Purified antibody in PBS with 0.PMID:33714988 05% sodium azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
40 kDa
Positive control :
Human SRY recombinant protein, NTERA-2, human cervical cancer tissue, human ovarian cancer tissue, HepG2.