Product Name :
ROR alpha Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
fhl2a antibody NR1F1 antibody Nuclear receptor ROR alpha antibody Nuclear receptor ROR-alpha antibody Nuclear receptor RZR-alpha antibody Nuclear receptor subfamily 1 group F member 1 antibody RAR related orphan receptor A antibody RAR related orphan receptor alpha antibody RAR-related orphan receptor A antibody Retinoid-related orphan receptor-alpha antibody 展开
Function :
Orphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5′-[AT][TA]A[AT][CGT]TAGGTCA-3′. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1.2059140-61-1 site Possible receptor for cholesterol or one of its derivatives.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human ROR alpha 151-250/523
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
Verify application:
WB, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.2313230-37-2 manufacturer Avoid repeated freeze/thaw cycles.PMID:33427568 The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
59 KDa
Positive control :
Widely expressed in a number of tissues. Expressed in both regulatory T-cells (Treg) and effector T-cells (Teff).