Product Name :
Phospho-Nucleophosmin (T199) Recombinant Rabbit Monoclonal Antibody [JE63-16]
Predicted band size :
33 kDa
Observed band size :
38 kDa
Synonyms:
B23 antibody MGC104254 antibody NO38 antibody NPM antibody NPM_HUMAN antibody NPM1 antibody Nucleolar phosphoprotein B23 antibody Nucleolar protein NO38 antibody Nucleophosmin (nucleolar phosphoprotein B23 numatrin) antibody Nucleophosmin antibody 展开
Function :
Nucleophosmin (NPM), also known as nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. NPM1 is associated with nucleolar ribonucleoprotein structures and binds single-stranded and double-stranded nucleic acids, but it binds preferentially G-quadruplex forming nucleic acids. It is involved in the biogenesis of ribosomes and may assist small basic proteins in their transport to the nucleolus. Its regulation through SUMOylation (by SENP3 and SENP5) is another facet of the protein’s regulation and cellular functions. It is located in the nucleolus, but it can be translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic phosphopeptide corresponding to residues surrounding Thr199 of Human Nucleophosmin.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE63-16
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.(Dtpby)NiBr2 manufacturer Aliquot store at -20℃.2869955-58-6 Chemscene Avoid repeated freeze / thaw cycles.PMID:33630204
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 33 kDa
Positive control :
HeLa cell lysate, HeLa treated with 100ng/mL Nocodazole for 17 hours cell lysate.